serotonin [5HT]-1B receptor; 5-hydroxytryptamine receptor 1B; 5-HT-1D-beta; 5-HT-1B; 5-HT1B; serotonin receptor 1B; serotonin 1D beta receptor; S12 (HTR1B, HTR1DB)

Function

• one of the several receptors for 5-hydroxytryptamine (serotonin)
• activity is mediated by G proteins that inhibit adenylate cyclase (Gi proteins)
• phosphorylated
• desensitization of the receptor may be mediated by its phosphorylation

Structure

• belongs to the G-protein coupled receptor 1 family
• palmitoylated

Compartment

cell membrane

More general terms

• serotonin [5HT]-1 receptor
• glycoprotein
• phosphoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3351
• OMIM: https://mirror.omim.org/entry/182131
• UniProt: http://www.uniprot.org/uniprot/P28222.html