keratin, type 2 cytoskeletal 3; cytokeratin-3; CK-3; keratin-3; K3; 65 kD cytokeratin (KRT3)

Function

• keratin-3 associates with keratin-12

Structure

• type 2 keratin
• heterotetramer of 2 type 1 & 2 type 2 keratins
• belongs to the intermediate filament family

Expression

cornea specific

Pathology

• defects in KRT3 are a cause of Meesmann corneal dystrophy

More general terms

• cytokeratin, epithelial keratins or soft alpha-keratins
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P12035.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3850
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3850
• OMIM: https://mirror.omim.org/entry/122100
• OMIM: https://mirror.omim.org/entry/148043