dehydrogenase/reductase SDR family member on chromosome X (DHRSXY, DHRSX, CXorf11, DHRS5X, UNQ6508/PRO21433)

Function

• meiotic pairing recombination (putative)

Structure

• belongs to the short-chain dehydrogenases/reductases (SDR) family

Genetics

• gene belongs to the pseudoautosomal region 1 (PAR1)
• PAR1 located at the termini of the long & short arms of the X & Y chromosomes
• region is essential for meiotic pairing recombination
• genes in the PAR1 region escape X inactivation
• deletion of the PAR1 region causes male sterility

More general terms

• dehydrogenase/reductase SDR family (DHRS)

Database

• UniProt: http://www.uniprot.org/uniprot/Q8N5I4.html