ATP-dependent RNA helicase DDX24; DEAD box protein 24 (DDX24)

Function

• ATP-dependent RNA helicase (putative)
• ATP + H2O = ADP + phosphate
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• belongs to the DEAD box helicase family, DDX24/MAK5 subfamily
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Expression

• ubiquitous
• most abundant in heart & brain, but with lowest levels in thymus & small intestine

More general terms

• DEAD box ATP-dependent helicase
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57062
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57062
• OMIM: https://mirror.omim.org/entry/606181
• UniProt: http://www.uniprot.org/uniprot/Q9GZR7.html