DEAD box protein 56; ATP-dependent RNA helicase DDX56; ATP-dependent 61 kD nucleolar RNA helicase (DDX56, NOH61)

Function

• may play a role in later stages of pre-ribosomal particle processing leading to mature 60S ribosomal subunits
• has intrinsic ATPase activity
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• may form homo-oligomeric complexes
• belongs to the DEAD box helicase family, DDX56/DBP9 subfamily
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

nucleus, nucleolus

Expression

• detected in heart, brain, liver, pancreas, placenta & lung

More general terms

• DEAD box ATP-dependent helicase

Database

• UniProt: http://www.uniprot.org/uniprot/Q9NY93.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=54606
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5460
• OMIM: https://mirror.omim.org/entry/608023