mitogen-activated protein kinase 4 (extracellular signal regulated kinase 3 related, ERK3-alpha, p63-MAPK, p64erk3, p55, p63, p64 MAP kinase, MAPK4, ERK4, PRKM4)

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Function

Cofactor: Mg+2 (putative)

Structure

Expression

  • high expression in heart & brain

Notes

  • mouse homolog may be p55mapk
  • not considered by some as bonefide MAP kinase

More general terms

References

  1. Pelech SL, Sanghera JS. Mitogen-activated protein kinases: versatile transducers for cell signaling. Trends Biochem Sci. 1992 Jun;17(6):233-8. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1323888
    Pelech SL, Sanghera JS. MAP kinases: charting the regulatory pathways. Science. 1992 Sep 4;257(5075):1355-6. No abstract available. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1382311
  2. Mohit AA, Martin JH, Miller CA. p493F12 kinase: a novel MAP kinase expressed in a subset of neurons in the human nervous system. Neuron. 1995 Jan;14(1):67-78. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7826642
  3. UniProt http://www.uniprot.org/uniprot/P31152.html

Database