beta-1,3-galactosyltransferase 5; beta-1,3-GalTase 5; beta3Gal-T5; b3Gal-T5; GalT5; UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 5; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5; beta-3-Gx-T5 (B3GALT5)
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Function
- catalyzes the transfer of gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)galNAc structure
- can use glycolipid LC3cer as an efficient acceptor
- protein modification; protein glycosylation
Structure
belongs to the glycosyltransferase 31 family
Compartment
Golgi membrane
Expression
- expressed in stomach, jejunum, colon, pancreas, small intestine, testis & gastrointestinal & pancreatic cancer cell lines
- very low expression in lung, liver, adrenal gland & peripheral blood leukocytes
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q9Y2C3.html
- ↑ GGDB; Note: Glycogene database http://riodb.ibase.aist.go.jp/rcmg/ggdb/homolog?cat=symbol&symbol=B3GALT5
- ↑ Functional Glycomics gateway - GTase Note: beta-1,3-galactosyltransferase 5 http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_432