beta-1,3-galactosyltransferase 4; beta-1,3-GalTase 4; beta3Gal-T4; b3Gal-T4; GAL-T2; GalT4; ganglioside galactosyltransferase; UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase (B3GALT4)
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Function
- role in GM1/GD1B/GA1 ganglioside biosynthesis
- protein modification; protein glycosylation
UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)- D-galactosyl-(1->4)-beta-D-glucosyl-N-acylsphingosine
<->
UDP + D-galactosyl-(1->3)-beta-N-acetyl-D-galactosaminyl- (N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine
Structure
belongs to the glycosyltransferase 31 family
Compartment
Golgi membrane
Expression
- expressed in heart, skeletal muscle & pancreas > brain, placenta, kidney, liver & lung
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/O96024.html
- ↑ GGDB; Note: Glycogene database http://riodb.ibase.aist.go.jp/rcmg/ggdb/homolog?cat=symbol&symbol=B3GALT4
- ↑ Functional Glycomics gateway - GTase Note: beta-1,3-galactosyltransferase 4 http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_431