GM1 ganglioside; monosialoganglioside

Introduction

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Gal-(B1,3)-GalNAc-(B1,4)-Gal-(B1,4)-Glc-Ceramide
                          |
                         (a2,3)-NANA

Oligomers or polymers (fibrils) of A4/42 in lipoprotein complexes associated with GM1 may be the initial precipitating species in neuritic plaques of Alzheimer's disease

Laboratory

• ganglioside GM1 Ab in serum
  • ganglioside GM1 IgG in serum
  • ganglioside GM1 IgM in serum
• ganglioside GM1 IgG in CSF
• ganglioside GM1 IgM in CSF

More general terms

• ganglioside

More specific terms

• asialoganglioside GM1 IgM in serum

Additional terms

• A4 amyloid peptide; beta-peptide
• GM1 gangliosidosis

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=451590