cytosolic 5'-nucleotidase 1B; autoimmune infertility-related protein; cN1B (NT5C1B, AIRP, FKSG85)

Function

• dephosphorylates the 5' & 2'(3')-phosphates of deoxyribonucleotides
• broad substrate specificity
• regulation of adenosine levels
• activated by ADP

Cofactor: Mg+2

Structure

belongs to the 5'-nucleotidase type 3 family

Compartment

cytoplasm

Alternative splicing

named isoforms=4

Expression

• expressed in testis, placenta, pancreas > heart, kidney, liver, lung

More general terms

• 5'nucleotidase (5'-ribonucleotide phosphohydrolase)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=100526
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=93034
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:100526
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:93034
• OMIM: https://mirror.omim.org/entry/610526
• UniProt: http://www.uniprot.org/uniprot/Q96P26.html