myosin-10; unconventional myosin-10 (MYO10, KIAA0799)

Function

• myosins are actin-based motor molecules with ATPase activity
• unconventional myosins serve in intracellular movements
• their highly divergent tails are presumed to bind to membrane compartments, which would be moved relative to actin filaments
• role in regions of dynamic actin
• interacts with ECM29

Structure

• contains 1 FERM domain
• contains 3 IQ domains
• contains 1 myosin head-like domain
• contains 1 MyTH4 domain
• contains 2 PH domains

More general terms

• unconventional myosin
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4651
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4651
• OMIM: https://mirror.omim.org/entry/601481
• UniProt: http://www.uniprot.org/uniprot/Q9HD67.html