interferon-stimulated 20 kDa exonuclease-like 2 (ISG20L2)

Function

• 3'-> 5'-exoribonuclease involved in ribosome biogenesis in the processing of the 12S pre-rRNA
• specificity for a 3'-end containing a free hydroxyl group

Structure

contains 1 exonuclease domain

Compartment

nucleus, nucleolus

More general terms

• exoribonuclease

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=81875
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:81875
• OMIM: https://mirror.omim.org/entry/611930
• UniProt: http://www.uniprot.org/uniprot/Q9H9L3.html