chromosomal translocation t11q23:15q14 (AML)
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Introduction
* chromosomal translocation t(11;15)(q23;q14) involving ZFYVE19 with MLL/HRX is associated with acute myeloblastic leukemia AML)
* chromosomal translocation t(11;15)(q23;q14) involving CASC5 with MLL/HRX is associated with acute myeloblastic leukemia (AML) translocation may give rise to a MLL-CASC5 fusion protein
More general terms
Additional terms
- acute myeloid leukemia (AML)
- myeloid/lymphoid, or mixed lineage, leukemia (MLL) gene, TRX1 gene, trithorax homolog, HRX gene or ALL1 gene
- zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain, ZFYVE19, MPFYVE)
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q96K21.html
- ↑ UniProt http://www.uniprot.org/uniprot/Q8NG31.html
Atlas of Genetics & Cytogenetics in Oncology & Haematology http://atlasgeneticsoncology.org/Genes/AF15q14ID318.html