chromosomal translocation t(10;14)(q11;q32)

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Introduction

Chromsomal translocation t(10;14)(q11;q32) with GOLGA5 generates the RET/GOLGA5 (PTC5) oncogene. May occur secondary to radiation exposure. Translocation associated with papillary thyroid carcinoma.

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References

  1. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 519
  2. UniProt http://www.uniprot.org/uniprot/P07949.html