chromosomal translocation t(9;18)(p13;q11.2) (acute lymphoblastic leukemia)

Introduction

• chromosomal translocation t(9;18)(p13;q11.2) involving ZNF521 with PAX5 is found in acute lymphoblastic leukemia

translocation generates the PAX5-ZNF521 oncogene consisting of N-terminus of PAX5 & C-terminus of ZNF521

More general terms

• chromosomal translocation

Additional terms

• neuronal PAS domain-containing protein 3 (neuronal PAS3, member of PAS protein 6, basic-helix-loop-helix-PAS protein MOP6, NPAS3, MOP6)