chromosomal translocation t(2;8)(p23;p11.2)
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Introduction
- chromosomal translocation t(2;8)(p23;p11.2 involving ASXL2 with MYST3 is a cause of therapy-related myelodysplastic syndrome
- the translocation generates a MYST3-ASXL2 fusion protein
More general terms
Additional terms
- histone acetyltransferase MYST3; MYST protein 3; MOZ, YBF2/SAS3, SAS2 & TIP60 protein 3; Runt-related transcription factor-binding protein 2; monocytic leukemia zinc finger protein; zinc finger protein 220 (MYST3, MOZ, RUNXBP2, ZNF220, KAT6A)
- myelodysplastic syndrome (MDS)
- polycomb group protein ASXL2 (ddditional sex combs-like protein 2, ASXL2, ASXH2, KIAA1685)