immunofixation electrophoresis (IFE)
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Indications
- monoclonal gammopathy
- allows for identification of monoclonal antibody in terms of immunoglobulin class (eg IgG, IgM, IgA) & immunoglobulin subclass (eg IgG1, IgG2 ...)
Procedure
- after separation of components by electrophoresis, addition of antibodies or antisera fix antigen-antibody complexes while unbound components are washed from gel
More general terms
More specific terms
References
- ↑ Fundamentals of Clinical Chemistry 3rd ed., N.W. Teitz ed., W.B. Saunders, 1988, pg 325
- ↑ Immunofix Electrophoresis Gel Laboratory Test Directory ARUP: http://www.aruplab.com/guides/ug/tests/0050272.jsp
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