follicular lichen planus; lichen planopilaris; Graham Little-Piccardi-Lassueur syndrome
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Introduction
follicular form of lichen planus
Etiology
Epidemiology
- rare
- women affected > men
- typical age of onset 40-60 years
Pathology
- lymphocyte mediated lichenoid perifollicular inflammation
Clinical manifestations
- perifollicular violaceous erythema & keratotic plugs
- lichen planus on the skin, nails, &/or mucosa may be present
- keratotic lichenoid follicular papules & plaques resulting in scarring alopecia
- non-scarring loss of pubic hair & axillary hair
* images[5]
Complications
- major psychological consequences
- relapses are common after local or systemic treatment
Management
- topical glucocorticoids, intralesional glucocorticoids, oral glucocorticoids[3]
- hydroxychloroquine[3]
- immunosuppressants[3]
More general terms
More specific terms
References
- ↑ Color Atlas and Synopsis of Clinical Dermatology, Common and Serious Diseases, 3rd ed, Fitzpatrick et al, McGraw Hill, NY, 1997, pg 267
- ↑ Assouly P, Reygagne P. Lichen planopilaris: update on diagnosis and treatment. Semin Cutan Med Surg. 2009 Mar;28(1):3-10 PMID: https://www.ncbi.nlm.nih.gov/pubmed/19341936
- ↑ 3.0 3.1 3.2 3.3 Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015
- ↑ Racz E, Gho C, Moorman PW, Noordhoek Hegt V, Neumann HA. Treatment of frontal fibrosing alopecia and lichen planopilaris: a systematic review. J Eur Acad Dermatol Venereol. 2013 Dec;27(12):1461-70 PMID: https://www.ncbi.nlm.nih.gov/pubmed/23531029
- ↑ 5.0 5.1 DermNet NZ. Lichen planopilaris (images) http://www.dermnetnz.org/hair-nails-sweat/lichen-planopilaris.html