protein SFI1 homolog (hSFI1, SFI1, KIAA0542)

Function

• role in the dynamic structure of centrosome-associated contractile fibers via its interaction with centrin CETN2
• interacts with centrin CETN2 (via C-terminus)

Structure

• CETN2-binding regions contain a conserved Trp in their C-terminal ends, which seem critical for interaction with CETN2
• belongs to the SFI1 family
• contains 6 HAT repeats

Compartment

• centrosome
• localized close to the centriole

Alternative splicing

named isoforms=8

Notes

uncertain whether Met-1 or Met-24 is the initiator

More general terms

• uncharacterized protein

Database

• UniProt: http://www.uniprot.org/uniprot/A8K8P3.html