connective-tissue activating peptide III

Function

• derived from platelet basic protein (PPBP) by proteolysis
• proteolytic removal of residues 1-9 from PPBP produces the active peptide connective tissue-activating peptide 3 (CTAP-3) (low-affinity platelet factor IV (LA-PF4))
• CTAP-3(1-81) is more potent than CTAP-3; both desensitize chemokine-induced neutrophil activation

More general terms

• platelet basic protein

Database

• OMIM: https://mirror.omim.org/entry/121010