tripartite motif-containing protein 5-alpha (trim5-alpha)

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Introduction

trim5-alpha of rhesus monkey inhibits HIV-1 replication (reverse transcriptase). trim5-alpha of human does NOT.

More general terms

Additional terms

References

  1. Journal Watch 24(7):56, 2004
    Stremlau M et al The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature 427:848, 2004 PMID: https://www.ncbi.nlm.nih.gov/pubmed/14985764