thyroid adenoma
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Introduction
Adenomas of the thyroid almost always present as solitary masses derived from follicular epithelium. Only rarely do the adenomas progress to malignant tumors.
Genetics
- chromosomal translocations t(2;3)(p21;p25) & t(2;7)(p21;p15) involving THADA have been observed in benign thyroid adenomas; the fusion events probably result in truncated THADA proteins
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References
- ↑ Cotran et al Robbins Pathologic Basis of Disease, 5th ed. W.B. Saunders Co, Philadelphia, PA 1994 pg 1134