idiopathic primary hypothyroidism; atrophic autoimmune thyroiditis
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Introduction
The most frequent cause of hypothyroidism in the US.
Etiology
blocking antibodies against TSH receptor
Genetics
association with HLA-DR3 & HLA-B8
Management
- thyroxine (thyroid hormone replacement)
Prognosis:
- auto-antibody may disappear spontaneously or with treatment
More general terms
References
- ↑ Cotran et al Robbins Pathologic Basis of Disease, 5th ed. W.B. Saunders Co, Philadelphia, PA 1994 pg 1125-26