chorea

Etiology

• Sydenham chorea with rheumatic fever
• Huntington's chorea
• neuroacanthocytosis
• choreoathetosis
• drug-induced chorea
• vascular chorea
• autoimmune chorea
  • systemic lupus erythematosus
  • antiphospholipid syndrome
• chorea gravidarum
• hyperglycemia

Clinical manifestations

• irregular, spasmodic, involuntary movements* of the limbs & muscles of the face, often accompanied with hypotonia (from the french choros: a dance)

* involuntary movements are not suppressible

Laboratory

• pregnancy test (female of child-bearing age)
• serum glucose
• also see
  • systemic lupus erythematosus
  • antiphospholipid syndrome
  • Huntington's chorea

Management

• also see Huntington's chorea
• tetrabenazine up to 100 mg/day or amantadine 300-400 mg/day or riluzole 200 mg/day
  • deutetrabenazine (Austedo) FDA-approved April 2017
  • valbenazine

More general terms

• movement disorder
• involuntary movement

More specific terms

• chorea gravidarum
• choreoathetosis
• Sydenham chorea (Saint Vitus dance)

Additional terms

• athetosis
• Huntington's disease; Huntington's chorea (progressive hereditary chorea)