aluminum osteodystrophy

Etiology

• chronic aluminum-containing antacids

Pathology

• low bone turnover state

Laboratory

• serum calcium: hypercalcemia
• serum PTH low
• serum 1,25-dihydroxyvitamin D3 low
• serum alkaline phosphatase levels are NOT increased
• complete blood count: microcytic anemia is common
• bone marrow biopby: iliac crest biopsy for diagnosis

Management

deferoxamine chelation

More general terms

• osteodystrophy