atrial septal aneurysm
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Etiology
- congenital heart disease
- occurs frequently in association with an patent foramen ovale
Epidemiology
- found in 28-40% of ischemic stroke patients < 55 years of age
Complications
- increased risk of embolic stroke*
- risk of stroke is especially associated with aneurysm excursions of > 10 mm
* reference 2 reports risk of recurrent stroke associated with both atrial septal aneurysm & patent foramen ovale, but not with either alone.
* proposed mechanisms include:
- paradoxical embolism from the venous circulation
- thrombosis within the aneurysm
- atrial arrhythmias
Management
- when an atrial septal defect is identified incidentally, no further evaluation or intervention is necessary[1]
- antiplatelet therapy is recommended for atrial septal aneurysm associated with cryptogenic stroke[1]
More general terms
Additional terms
References
- ↑ 1.0 1.1 1.2 Medical Knowledge Self Assessment Program (MKSAP) 11, 17 American College of Physicians, Philadelphia 1998, 2015
- ↑ Journal Watch 22(2):11, 2002 Mas JL1, Arquizan C, Lamy C et al Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both. N Engl J Med. 2001 Dec 13;345(24):1740-6. PMID: https://www.ncbi.nlm.nih.gov/pubmed/11742048
- ↑ Burger AJ, Sherman HB, Charlamb MJ. Low incidence of embolic strokes with atrial septal aneurysms: A prospective, long-term study. Am Heart J. 2000 Jan;139(1 Pt 1):149-52. PMID: https://www.ncbi.nlm.nih.gov/pubmed/10618576