atopic state

Introduction

Inherited tendency to develop type 1 hypersensitivity reactions.

• triad of atopy
  • allergic asthma
  • allergic rhinitis
  • atopic dermatitis
• anaphylactoid reactions to drugs
• many urticarial reactions

Epidemiology

• individuals are genetically predisposed to asteatotic dermatitis in the winter & miliaria-like reactions (prickly heat) in the summer
• more common among children who are born in the U.S. than among those who move here

Genetics

• associated with polymorphisms in PLA2G7

Complications

• disease interaction(s) asthma, smoking & atopy

More general terms

• pathologic process

Additional terms

• asteatotic dermatitis; eczema craquelatum; xerotic eczema; winter itch
• atopic dermatitis (atopic eczema)
• miliaria rubra (prickly heat)
• triad of atopy
• type 1 hypersensitivity; immediate hypersensitivity (allergy)