spindle-assembly checkpoint

Introduction

Prevents onset of anaphase until all chromosomes are properly aligned at the metaphase plate.

Components:

• MAD1L1

More general terms

• biochemistry

Components

• mitotic spindle assembly checkpoint protein MAD1 (mitotic arrest deficient-like protein 1, MAD1-like 1, mitotic checkpoint MAD1 protein-homolog, HsMAD1, hMAD1, Tax-binding protein 181, MAD1L1, MAD1, TXBP181)