gray platelet syndrome
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Pathology
- congenital platelet defects
- absence of alpha granules
- low beta-thromboglobulin
- low platelet factor 4
Clinical manifestations
- moderate rather than severe bleeding disorder[1]
Complications
Management
- platelet transfusions for active bleeding as needed
- epsilon-aminocaproic acid for active bleeding as needed[1]
More general terms
Additional terms
- beta-thromboglobulin 1 (TGB1, THBGB1)
- platelet factor 4; PF-4; C-X-C motif chemokine 4; iroplact; oncostatin-A (PF4, CXCL4, SCYB4)
References
- ↑ Jump up to: 1.0 1.1 1.2 Medical Knowledge Self Assessment Program (MKSAP) 11, 17, 18. American College of Physicians, Philadelphia 1998, 2015, 2018.