treatment failure, pneumonia

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^[1]^[2]

Etiology

inadequate antibiotic therapy
resistant organism
- empiric quinolone therapy may mask active tuberculosis^[2]
inadequate blood levels of antibiotic(s)
non-compliance
unusual pathogen
drug hypersensitivity
Clostridium difficile (pseudomembranous) colitis
complication:
poor host defense
- endobronchial obstruction
- life-threatening comorbidity
incorrect diagnosis (i.e. non-infectious etiology)
- congestive heart failure
- carcinoma of the lung
- pulmonary embolism
- inflammatory conditions
  - Wegener's granulomatosis
  - hypersensitivity pneumonitis
- drug-induced pneumonitis

More general terms

treatment failure

Additional terms

pneumonia (PNA)

References

↑ Harrison's Principles of Internal Medicine, 13th ed. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 1187
↑ ^{Jump up to: 2.0} ^2.1 Journal Watch 22(15):117, 2002 Dooley KE et al, Clin Infect Dis 34:1607, 2002

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