Paranaud's syndrome (dorsal midbrain syndrome)

Etiology

• damage to the posterior commissure
  • hydrocephalus resulting from aqueductal stenosis
  • pineal region tumors (germinoma, pineoblastoma)
  • cysticercosis
  • stroke

Clinical manifestations

• ocular gaze palsy (supranuclear)
  • inability to look up
  • pupils with slow reaction to light & brisk convergence
  • eyelid retraction, no ptosis
  • downward ocular deviation

More general terms

• syndrome

Additional terms

• Parinaud, Henri
• posterior commissure