Tiotropium: Influence on the Perception of the Improvement in Routine Activities Objectified by a Numerical Scale (TIPHON)

Introduction

9 month, placebo-controlled trial

554 patients with COPD

St. George Respiratory Questionnaire (SGRQ) used to assess quality of life measures using a 0-100 point scale. Visually-Simplified Respiratory Questionnaire (VSRQ) also used

FEV1 & FVC also measured

Results:

• after 9 months, 59% of Tiotropium group with 4 point improvement in SGRQ vs 48% in placebo group

More general terms

• clinical trial

Additional terms

• tiotropium (Spiriva, Respimat)