multicystic renal dysplasia (MRD); pelviureteric junctional obstruction (PUJO)

Pathology

• hydronephrosis

Genetics

• associated with defects in the CDC5L gene
  • chromosomal translocation t(6;19)(p21;q13.1) involving CDC5L with USF2 is found in multicystic renal dysplasia

More general terms

• renal dysplasia
• genetic disease of the kidney

Additional terms

• cell division cycle 5-like protein; Cdc5-like protein; Pombe cdc5-related protein (CDC5L, KIAA0432, PCDC5RP)

Database

• OMIM: https://mirror.omim.org/entry/143400