hereditary lymphedema 2 (Meige lymphedema)

Genetics

• autosomal dominant
• associated with defects in FOXC2

Clinical manifestations

• chronic disabling condition
• onset usually around puberty
• swelling of the extremities due to altered lymphatic flow
• recurrent local infections
• physical impairment

More general terms

• lymphedema
• genetic disease of the lymphatic system

Database

• OMIM: https://mirror.omim.org/entry/153200