cyclophosphamide/vincristine (Oncovin)/prednisone/procarbazine (C-MOPP)

Introduction

1st successful regimen to treat large-cell lymphoma.

Used to treat follicle center lymphoma, grade II

More general terms

• antineoplastic combination (combination chemotherapy)

Additional terms

• follicle center lymphoma, grade II (follicular mixed small & large cell lymphoma)
• large cell lymphoma

Components

• vincristine; 22-oxovincaleukoblastine; leurocristine (Oncovin, Vincasar PFS)
• cyclophosphamide (Cytoxan, Neosar, Procytox {Canadian}) [CPM, CTX, CYT, NSC 26271]
• procarbazine (Matulane, Natulan, ibenzmethyzin)
• prednisone (Deltasone, Orasone, Liquid Pred, Meticortin, Rayos)