brain microhemorrhage; brain microbleed; cerebral microhemorrhage

^[1]^[2]^[3]

Etiology

increased risk of dementia^[3] with
- mixed subcortical & lobar microbleeds (RR=1.99)
- lobar-only microbleeds (RR=1.96)
- cortical superficial siderosis (RR=2.57)
- >= 3 cerebral microbleeds of any pattern (RR=1.92)^[3]

↑ Geriatric Review Syllabus, 9th edition (GRS9) Medinal-Walpole A, Pacala JT, Porter JF (eds) American Geriatrics Society, 2016
↑ Haley KE, Greenberg SM, Gurol ME. Cerebral microbleeds and macrobleeds: should they influence our recommendations for antithrombotic therapies? Curr Cardiol Rep. 2013 Dec;15(12):425. Review. PMID: https://pubmed.ncbi.nlm.nih.gov/24122195 Free PMC Article
↑ ^3.0 ^3.1 ^3.2 Lou N Tiny Blood Smidges in the Brain: Amount and Location Tied to Dementia. Neuroimaging findings believed to arise from distinct pathologies. MedPage Today. February 27, 2026 https://www.medpagetoday.com/neurology/dementia/120086
Vuong RQ, Morrill VN, Graff-Radford J et al Associations Between Cerebral Microbleed Patterns and Incident Dementia: The ARIC-Neurocognitive Study. Stroke. 2026 Feb 27. PMID: https://pubmed.ncbi.nlm.nih.gov/41757413 https://www.ahajournals.org/doi/10.1161/STROKEAHA.125.052926