distal acquired demyelinating symmetric neuropathy (DADS)
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Etiology
Clinical manifestations
- symmetric, predominantly motor impairment without ataxia & tremor
- preserved proprioception
Laboratory
- elevated CSF protein - case report: 340 mg/dL (12-60 mg/dL)[2]
Diagnostic procedures
- electromyography
- absence of compound muscle action potentials over the feet &lower leg muscles[2]
- nerve conduction study
- preserved sural sensory nerve action potential
- decrease in evoked electrical excitability at site of femoral nerve stimulation[2]
Management
- case report: refractory to treatment[2]
More general terms
References
- ↑ Katz JS, Saperstein DS, Gronseth G, Amato AA, Barohn RJ. Distal acquired demyelinating symmetric neuropathy. Neurology. 2000 Feb 8;54(3):615-20. PMID: https://www.ncbi.nlm.nih.gov/pubmed/10680792 https://www.neurology.org/doi/10.1212/wnl.54.3.615
- ↑ 2.0 2.1 2.2 2.3 2.4 Khodulev VI, Ponomarev VV, Stepanova JI. Distal Acquired Demyelinating Symmetric Neuropathy Associated with Decreased Electrical Excitability of the Femoral Nerves. Maedica (Bucur). 2021 Dec;16(4):707-712. PMID: https://www.ncbi.nlm.nih.gov/pubmed/35261675 PMCID: PMC8897776 Free PMC article.