ristocetin
Jump to navigation
Jump to search
Introduction
An antibiotic produced by fermentation of Amycolatopis orientalis subspecies lurida, comprising two substances ristocetin A & ristocetin B.
Ristocetin-induced agglutination of platelets requires a cofactor found in serum. That cofactor is von-Willebrand's factor (vWF). As a pharmaceutical agent:
Indications
- Staphylococcal & Enterococcal infections refractory to other antibiotics
Antimicrobial activity
More general terms
Additional terms
- ristocetin cofactor activity
- von Willebrand factor; vWF; ristocetin cofactor; factor VIII related antigen; contains: von Willebrand antigen 2 (VWF, F8VWF)