gepotidacin

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Indications

* non-inferior to nitrofurantoin for treatment of uncomplicated UTIs

Dosage

  • 1500 mg PO BID for 5 days

Antimicrobial activity

  • common uropathogens, including clinically important drug-resistant organisms

Adverse effects

Mechanism of action

More general terms

References

  1. Wagenlehner F, Perry CR, Hooton TM et al Oral gepotidacin versus nitrofurantoin in patients with uncomplicated urinary tract infection (EAGLE-2 and EAGLE-3): two randomised, controlled, double-blind, double- dummy, phase 3, non-inferiority trials. Lancet. 2024 Feb 8:S0140-6736(23)02196-7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/38342126