SARS-CoV2 breathalyzer
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Indications
- rapid detection of SARS-CoV2
Clinical significance
- detects SARS-CoV2 aerosols in two exhaled breaths with results in < 60 seconds
- electrochemical biosensor directly detects the virus itself vs a surrogate or signature of the virus
- sensitive 10 viral particles in a sample
Mechanism of action
- integrates a hand-held breath aerosol collector & a SARS-CoV2 spike-protein specific nanobody bound to a micro-immunoelectrode biosensor
biosensor detects oxidation of tyrosine present in SARS-CoV2 viral particles
* llama-derived
More general terms
References
- ↑ Ghumra DP, Shetty N, McBrearty KR et al Rapid Direct Detection of SARS-CoV-2 Aerosols in Exhaled Breath at the Point of Care. ACS Sens. 2023, July 27 PMID: https://www.ncbi.nlm.nih.gov/pubmed/37498298 https://pubs.acs.org/doi/10.1021/acssensors.3c00512