drug interaction(s) of theophylline with fluoroquinolone
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Drug interactions
- coadministration of theophylline with fluoroquinolone (CYP1A2 inhibitors), increases serum concentration of theophylline & potentiates its toxicity
- risk is ~2 fold
Management
- select antibiotics other than fluoroquinolone for patients on theophylline
More general terms
References
- ↑ Antoniou T, Gomes T, Mamdani MM, Juurlink DN. Ciprofloxacin-induced theophylline toxicity: a population-based study. Eur J Clin Pharmacol. 2011 May;67(5):521-6. Epub 2011 Jan 14. PMID: https://www.ncbi.nlm.nih.gov/pubmed/21234553