HIV1/HIV2 Ab differentiation assay

Indications

• positive HIV 1+2 Ab & HIV1 p24 Ag in serum (screening test)

Clinical significance

• distinguishes HIV1 from HIV2 or suggests false positive screening test
  • positive HIV 1+2 Ab & HIV1 p24 Ag in serum
    • if negative differentiation assay, suggests HIV1 p24 Ag or false positive screening test for HIV1
  • a negative HIV1 nucleic acid amplification test confirms a false positive screening test for HIV1
  • a positive HIV nucleic acid amplification test confirms acute HIV1 infection*

* MKSAP20 does not seem to acknowlege the difference between HIV1 nucleic acid amplification & HIV nucleic acid amplification testing whereas OpenEvidence does

More general terms

• HIV laboratory testing