remote ischemic conditioning

^[1]^[2]

Indications

remote ischemic conditioning may improve neurologic function post ischemic stroke^[1]
of no benefit^[2]

involves repeated occlusion/release cycles on bilateral upper limb arteries^[1]
inflatable blood pressure cuff on 1 upper extremity <= 200 mm Hg for 5 minutes then 5 minutes of cuff deflation (5 cycles), started in ambulance, repeated at least once in hospital & for a subset twice a day for 7 days^[2]

↑ ^1.0 ^1.1 ^1.2 Chen HS, Cui Y, Li XQ et al Effect of Remote Ischemic Conditioning vs Usual Care on Neurologic Function in Patients With Acute Moderate Ischemic Stroke. The RICAMIS Randomized Clinical Trial. JAMA. 2022;328(7):627-636. PMID: https://www.ncbi.nlm.nih.gov/pubmed/35972485 https://jamanetwork.com/journals/jama/fullarticle/2795267
↑ ^2.0 ^2.1 ^2.2 Blauenfeldt RA, Hjort N, MD, Valentin JB et al Remote Ischemic Conditioning for Acute Stroke. The RESIST Randomized Clinical Trial. JAMA. 2023;330(13):1236-1246. PMID: https://www.ncbi.nlm.nih.gov/pubmed/37787796 https://jamanetwork.com/journals/jama/fullarticle/2810034