tirbanibulin (Klisyri)
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Introduction
Indecations:
- treatment of actinic keratosis on the face or scalp
Dosage
- 1% once daily for 3 or 5 days
1% topical ointment
Mechanism of action
- mitotic inhibitor
- inhibits tubulin polymerization & Src kinase signalling
More general terms
References
- ↑ RxNorm
- ↑ Wikipedia: Tirbanibulin https://en.wikipedia.org/wiki/Tirbanibulin
- ↑ Blauvelt A, Kempers S, Lain E et al Phase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis. N Engl J Med 2021; 384:512-520. Feb 11 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33567191 https://www.nejm.org/doi/full/10.1056/NEJMoa2024040