small cysteine & glycine repeat-containing protein 4; keratin-associated protein 28-4 (SCYGR4, KRTAP28-4)

Function

• in the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), essential for the formation of a rigid & resistant hair shaft through extensive disulfide bonds -matrix proteins include the high-sulfur & high-glycine-tyrosine keratins

Structure

belongs to the KRTAP type 28 family

Notes

• human have a similar number of genes as other primates despite relative hairlessness of humans

More general terms

• ketatin-associated protein (KRTAP)

Database

• UniProt: http://www.uniprot.org/uniprot/A0A286YEV6.html