small cysteine & glycine repeat-containing protein 6; keratin-associated protein 28-6 (SCYGR6, KRTAP2-6)
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Function
- in the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), essential for the formation of a rigid & resistant hair shaft through extensive disulfide bonds -matrix proteins include the high-sulfur & high-glycine-tyrosine keratins
Structure
belongs to the KRTAP type 28 family
Notes
- human have a similar number of genes as other primates despite relative hairlessness of humans