relugolix

Indications

• androgen-deprivation therapy for prostate cancer
• used in Japan for treatment of uterine fibroids

Dosage

• loading dose 360 mg PO, then 120 mg PO QD

Monitor

• serum testosterone

Mechanism of action

• gonadotropin-releasing hormone antagonist

More general terms

• antineoplastic endocrine agent

Component of

• estradiol/norethindrone/relugolix