curare

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Introduction

An extract of plants, Strychnos toxifera & other species & Chondodendron tomentosum. Alkoloids present in the extract, curarine from Strychnos & tubocurarine from Chondodendron induce non-depolarizing paralysis at the neuromuscular junction after intravenous injection by competitive inhibition of nicotinic receptors.

More general terms

References

  1. Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999
  2. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996 pg 178