enfortumab vedotin (Padcev)
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Indications
- locally advanced or metastatic urothelial cancer (bladder cancer) unresponsive to previous treatment
Adverse effects
- most common
- other
- rash (48%)
- peripheral neuropathy (50%)
- hyperglycenia (11%)
Mechanism of action
- targets nectin-4
More general terms
Additional terms
References
- ↑ Susman E MedPage Today. June 4, 2019 https://www.medpagetoday.com/meetingcoverage/asco/80226
Petrylak D et al EV-201: Results of enfortumab vedotin monotherapy for locally advanced or metastatic urothelial cancer previously treated with platinum and immune checkpoint inhibitors. American Society of Clinical Oncology (ASCO) 2019; Abstract LBA4505. - ↑ Bankhead C Survival Boost in Bladder Cancer With Antibody-Drug Conjugate - Four-month absolute improvement with enfortumab vedotin in previously treated disease. MedPage Today February 12, 2021 https://www.medpagetoday.com/meetingcoverage/mgucs/91192