ubiquitin C-terminal hydrolase in blood
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Indications
- assessment of need for CT of brain in adults with mild traumatic brain injury (concussion)
Clinical significance
- released from the brain into blood
- can be measured within 12 hours of head injury
Methods
- 3-4-hour turnaround time
More general terms
Additional terms
- glial fibrillary acidic protein (GFAP) in blood/plasma/serum
- ubiquitin C-terminal hydrolase; UCH; ubiquitin thiolesterase; ubiquitin-specific processing protease; deubiquitinating enzyme
References
- ↑ Brooks M FDA Clears First Blood Test to Aid in Concussion Diagnosis. Medscape - Feb 14, 2018. https://www.medscape.com/viewarticle/892683
FDA News Release. Feb 14, 2018 FDA authorizes marketing of first blood test to aid in the evaluation of concussion in adults. https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm596531.htm